Precision Medicine in Incident Diabetic Foot Complications

PhD defence by Abhilasha Akerkar

Assessment Committee

Professor, Chief Consultant, Dr Med Sci Ole Lander Svendsen, Department of Clinical Medicine, Internal Medicine, University of Copenhagen (Chairperson)
Consultant & Sr. Lecturer, Univ. of Sheffield, UK Dinesh Selvarajah, Senior Lecturer, Univ. of Sheffield, Honorary Consultant Physician in Diabetes, Sheffield Teaching Hospital NHS Foundation Trust, UK
Researcher, MD, PhD Diana Hedevang Christensen, Researcher, Dept. of Clinical Epidemiology (DCE), Aarhus University Hospital (AUH; 20%) & Specialist in endocrinology, Dept. of Endocrinology and Internal Medicine, AUH (80%) and Dept. of Internal Medicine, Regional Hospital Horsens

Supervisors

Professor Tarun Veer Singh Ahluwalia
Post.doc, ph.d., MD Christian Stevns Hansen
Associate Professor Adam Hulman
Clinical Professor Peter Rossing
Postdoc, ph.d., MSc Pernille Falberg Rønn

Department

Department of Biology

Place

The defence is conducted as a hybrid defence.

To attend the defence in person:
Building: Steno Diabetes Center Copenhagen, Room: Reception area,
Borgmester Ib Juuls Vej 83,, 2730 Herlev, Denmark

To attend the defence online:
Please follow the link to attend the defence online: https://teams.microsoft.com/meet/3508454106972409?p=zXyHqtGX4VwruVkWe5
MeetingID, if relevant: 350 845 410 697 240 9
Password, if relevant: UV6Jn7KA

Email address to gain access to the thesis: abhilashakerkar@gmail.com.
You will either receive a copy of the thesis or be informed where you can read a physical copy.
Recipients of copies of the thesis are not allowed to share or distribute it due to copyright compliance.

Short description of the thesis

Diabetic foot complications are multifactorial conditions affecting the feet of people with diabetes, typically developing as a consequence of long-term diabetes-related damage. Precision medicine in incident diabetic foot complications would involve understanding its distribution, developing algorithms for its probability-based prediction and using relevant clinical biomarkers to possibly give new insights into its developmental pathway. All three studies conducted in this thesis are register-based studies, which used data from electronical health records at Steno Diabetes Center Copenhagen, with additional data linked from Danish national registers. With these studies in the thesis, we aimed to enhance our understanding of the first diabetic foot complication for its timely prevention in different risk groups of individuals with diabetes.